Transdermal Anti-Emetics
Topical application of anti-emetics in a gel formulation provides a rapid onset and offers an effective alternative to oral administration. Oral surgeons have found this formulation to be particularly useful.
Promethazine is commonly compounded for topical or transdermal application to treat nausea, vomiting, and vertigo, but this preparation may be used as an antiemetic for cases ranging from chemotherapy to motion sickness. The dose is typically 25mg for adults, and the dose is decreased for children. The gel is applied to an area of soft skin, such as the inside of the wrist or arm, the side of the torso, or the inside of the thigh. For children, the gel is often applied to the inside of one wrist, and then the wrists are rubbed together. US Pharmacist, August 1999; 74-5
Other dosage forms include suppositories and lollipops.
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CD Whyte Ridge Pharmacy
123 G Scurfield Blvd., Winnipeg, MB R3Y 1L6
Phone: 204-488-1819 · Fax: 204-489-2828
CinDen Pharmacy
1600 Pembina Hwy., Winnipeg, MB R3T 5Z2
Phone: 204-452-7989 · Fax: 204-452-7585
