Andropause : Goals of Therapy

Goals of Testosterone Replacement Therapy in Adult Hypogonadal Men (age 50 or older)

• Improvement in psychological well-being and mood
• Improvement in erectile dysfunction
• Improvement in libido
• Increased muscle mass
• Increased strength and stature
• Preservation of bone mass
• Possible decrease in cardiovascular risk

A man may be considered hypogonadal at any age if total testosterone is less than 200 ng/dl, or bioavailable testosterone is less than 60 ng/dl. Basaria and Dobs of Johns Hopkins University recommend that elderly men with symptoms of hypogonadism and a total testosterone level < 300ng/dl should be started on hormone replacement.