Wound Care : Skin Irritation

Numerous topical preparations containing cholestyramine or sucralfate (creams, adhesive pastes, enemas, suppositories) have been used for their protectant properties or for treatment of a variety of dermatologic and mucosal problems, including oral and esophageal ulcers, peristomal and perineal excoriation, decubitus ulcers, and radiation-induced rectal and vaginal ulcerations, and second and third degree burns.

Ann Pharmacother 1996 Sep;30(9):954-6

Cholestyramine ointment to treat buttocks rash and anal excoriation in an infant. White CM, Gailey RA, Lippe S. Albany College of Pharmacy, NY 12208, USA.

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Dis Colon Rectum 1987 Feb;30(2):106-7

Cholestyramine ointment in the treatment of perianal skin irritation following ileoanal anastomosis. Moller P, Lohmann M, Brynitz S.

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Clin Exp Dermatol. 2000 Nov;25(8):584-8

Topical sucralfate in the management of peristomal skin disease: an open study. Lyon CC, Stapleton M, Smith AJ, Griffiths CE, Beck MH. Dermatology Centre, University of Manchester, and the Pharmacy and the Department of Stoma-Care, Hope Hospital, Salford, UK.

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Burns. 2001 Aug;27(5):465-9

Topical use of sucralfate cream in second and third degree burns. Banati A, Chowdhury SR, Mazumder S. Department of Plastic Surgery and Burns Research Unit. Institute of Post Graduate Medical Education and Research, 220, Acharya Jagadish Chandra Bose Road, -700 020, Calcutta, India.

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